Prolotherapy is an injection of dextrose solution (sugar water) as opposed to cortisone. It has been available for many years, Chronic and acute pain patients, as well as athletes with sports injuries who are seeking an alternative to surgery, arthroscopy, cortisone shots, non-steroidal anti-inflammatories, or pain medications, may choose to consider prolotherapy.

Prolotherapy stimulates the body to repair the injured area when the body’s natural healing process is not able to do the job on its own. The basic concept of Prolotherapy is simple. The body heals injuries via inflammation response. Prolotherapy stimulates a mild local inflammatory reaction by injecting dextrose (sugar solution) as a local irritant. This local irritant triggers a ‘healing cascade’ resulting in the deposition of new collagen, the material of which ligaments, tendons, and cartilage are comprised. The typical course is a series of three to five injection at two week intervals, and relatively protecting the injured area from stresses during the healing period. A single injection or two is not effective. Prolotherapy success rates have been high, with few side-effects.

Health First Medical Center consults and works with Dr. Albert Franchi of Boston Prolotherapy. With his permission we bring you his online video library covering a multitude of topics about Prolotherapy.


Prolotherapy has been shown to be safe and very effective in treating almost every joint in the body. Most commonly: Knees, Shoulders, Hips, Necks, Backs, Ankles, Feet, Elbows, Hands and Wrists.

It is extremely effective in treating any torn ligament or tendon in the body including: Rotator Cuff, Plantar Fasciitis, Tennis and Golf Elbow (Tommy John Injury), Hamstrings, Groin Strains and Pubic Instability.

Joint instabilities such as Sacroiliac Instabilities, Unstable Ankles, Chronic Shoulder Dislocations, Dislocated Knee Caps, Bicep Tendon Instability, and Hyper Mobility Syndrome (Ehlers-Danlos Syndrome).

Prolotherapy is not for everyone. Prolotherapy is not indicated for herniated discs, spinal stenosis, or carpal tunnel syndrome. Prolotherapy will not work for most torn menisci.

Conditions responsive to prolotherapy include: Osteoarthritis Tendinitis Cartilage Injury Knee Pain Shoulder Pain Rotator Cuff Elbow Pain Tennis Elbow Hip Pain Ankle Sprains Plantar Fasciitis Arthritis of the Hand Foot Pain Sacroiliac Pain Wrist Pain